Analytical Method

Development of an Analytical Method for Unsaturated Disaccharides from Heparan Sulfate Using Dansylhydrazine Derivatization and High-Performance Liquid Chromatography with Fluorescence Detection

Takamasa Ishii¹, Ayaka Aijima¹, Nae Yokota¹, Kengo Hirai¹, Kyohei Higashi², Yusuke Iwasaki¹, Rie Ito¹, Nobuaki Higashi³, Hiroshi Akiyama¹

Affiliations expand

PMID: 38811191
DOI: 10.1248/bpb.b24-00194

Biosynthetic production of anticoagulant heparin polysaccharides through metabolic and sulfotransferases engineering strategies

Jian-Qun Deng,¹Yi Li,¹Yu-Jia Wang,¹Ya-Lin Cao,¹Si-Yu Xin,¹Xin-Yu Li,¹Rui-Min Xi,¹Feng-Shan Wang,^1,2 and Ju-Zheng Sheng^1,2

Nat Commun. 2024; 15: 3755.

Published online 2024 May 4. doi: 10.1038/s41467-024-48193-5